Thomas Holland, MD, MSc-GH
Department of Medicine
Department of Medicine
Dr. Thomas Holland completed the Global Health Fellowship Pathway in 2011 and is currently Assistant Professor of Medicine at Duke University Medical Center. He concurrently completed a Fogarty International Clinical Research Fellowship in Eldoret, Kenya where he investigated the prevalence of rheumatic heart disease. He received his undergraduate degree from Princeton University in Evolutionary Biology and his MD from Wake Forest University before completing Internal Medicine residency and Infectious Diseases fellowship training at Duke. His earliest interest in global health was born out of a year spent teaching in a secondary school in Lilongwe, Malawi.
During his internal medicine residency Dr. Holland was selected to spend several months working with a primarily Aboriginal population in the Australian Outback on a Global Health Rotation. This experience further crystallized his commitment to a career spent advancing the care of underserved populations. He subsequently embarked upon Infectious Disease specialty training and simultaneously joined the Global Health Fellowship at Duke. The Global Health Pathway has equiped Dr. Holland as an infectious disease clinician as well as providing multidisciplinary training, via the Master of Science in Global Health, in biostatistics, economics, ethics, research methods, and politics of global health.
Dr. Holland seeks to apply this multidisciplinary training to a problem of fundamental importance in the developing world. In rheumatic heart disease in Kenya, there is an intersection of the clinical worlds of acute infectious disease and chronic cardiovascular disease, as well as the challenge of improving upon currently inadequate epidemiologic data.
Deck, DH, Jordan, JM, Holland, TL, Fan, W, Wikler, MA, Sulham, KA, and Ralph Corey, G. "Erratum to: Single-Dose Oritavancin Treatment of Acute Bacterial Skin and Skin Structure Infections: SOLO Trial Efficacy by Eron Severity and Management Setting." Infectious diseases and therapy (August 26, 2016).
Lumsden, RH, Akwanalo, C, Chepkwony, S, Kithei, A, Omollo, V, Holland, TL, Bloomfield, GS, and O'Meara, WP. "Clinical and geographic patterns of rheumatic heart disease in outpatients attending cardiology clinic in western Kenya." International journal of cardiology 223 (August 4, 2016): 228-235.
Knirsch, C, Alemayehu, D, Botgros, R, Comic-Savic, S, Friedland, D, Holland, TL, Merchant, K, Noel, GJ, Pelfrene, E, Reith, C, Santiago, J, Tiernan, R, Tenearts, P, Goldsack, JC, and Fowler, VG. "Improving Conduct and Feasibility of Clinical Trials to Evaluate Antibacterial Drugs to Treat Hospital-Acquired Bacterial Pneumonia and Ventilator-Associated Bacterial Pneumonia: Recommendations of the Clinical Trials Transformation Initiative Antibacterial Drug Development Project Team." Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 63 Suppl 2 (August 2016): S29-S36.
Deck, DH, Jordan, JM, Holland, TL, Fan, W, Wikler, MA, Sulham, KA, and Ralph Corey, G. "Single-Dose Oritavancin Treatment of Acute Bacterial Skin and Skin Structure Infections: SOLO Trial Efficacy by Eron Severity and Management Setting." Infectious diseases and therapy (July 2016).
Maina, AN, Farris, CM, Odhiambo, A, Jiang, J, Laktabai, J, Armstrong, J, Holland, T, Richards, AL, and O'Meara, WP. "Q Fever, Scrub Typhus, and Rickettsial Diseases in Children, Kenya, 2011-2012." Emerging infectious diseases 22, no. 5 (May 2016): 883-886. Open Access Copy
Lane, S, Johnston, K, Sulham, KA, Syed, I, Pollack, CV, Holland, T, and Nathwani, D. "Identification of Patient Characteristics Influencing Setting of Care Decisions for Patients With Acute Bacterial Skin and Skin Structure Infections: Results of a Discrete Choice Experiment." Clinical Therapeutics 38, no. 3 (March 2016): 531-544.e9. Full Text
Holland, TL, Baddour, LM, Bayer, AS, Hoen, B, Miro, JM, and Fowler, VG. "Infective endocarditis." Nature reviews. Disease primers 2 (January 2016): 16059-.
Bergin, SP, Holland, TL, Fowler, VG, and Tong, SY. "Bacteremia, Sepsis, and Infective Endocarditis Associated with Staphylococcus aureus." Current topics in microbiology and immunology (December 8, 2015).
Tong, SY, Davis, JS, Eichenberger, E, Holland, TL, and Fowler, VG. "Staphylococcus aureus infections: epidemiology, pathophysiology, clinical manifestations, and management." Clinical microbiology reviews 28, no. 3 (July 2015): 603-661. (Review)
Bostwick, AD, Zhang, C, Manninen, K, Touchberry, J, Greene, SR, and Holland, TL. "Bacteremia Caused by Kerstersia gyiorum." Journal of clinical microbiology 53, no. 6 (June 2015): 1965-1967.
O'Meara, WP, Mott, JA, Laktabai, J, Wamburu, K, Fields, B, Armstrong, J, Taylor, SM, MacIntyre, C, Sen, R, Menya, D, Pan, W, Nicholson, BP, Woods, CW, and Holland, TL. "Etiology of pediatric fever in western Kenya: a case-control study of falciparum malaria, respiratory viruses, and streptococcal pharyngitis." The American journal of tropical medicine and hygiene 92, no. 5 (May 2015): 1030-1037.
Arnold, CJ, Johnson, M, Bayer, AS, Bradley, S, Giannitsioti, E, Miró, JM, Tornos, P, Tattevin, P, Strahilevitz, J, Spelman, D, Athan, E, Nacinovich, F, Fortes, CQ, Lamas, C, Barsic, B, Fernández-Hidalgo, N, Muñoz, P, and Chu, VH. "Candida infective endocarditis: an observational cohort study with a focus on therapy." Antimicrobial agents and chemotherapy 59, no. 4 (April 2015): 2365-2373.
Chirouze, C, Alla, F, Fowler, VG, Sexton, DJ, Corey, GR, Chu, VH, Wang, A, Erpelding, ML, Durante-Mangoni, E, Fernández-Hidalgo, N, Giannitsioti, E, Hannan, MM, Lejko-Zupanc, T, Miró, JM, Muñoz, P, Murdoch, DR, Tattevin, P, Tribouilloy, C, and Hoen, B. "Impact of early valve surgery on outcome of Staphylococcus aureus prosthetic valve infective endocarditis: analysis in the International Collaboration of Endocarditis-Prospective Cohort Study." Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 60, no. 5 (March 2015): 741-749.
Holland, TL, and Fowler, VG. "Diagnosing endocarditis in patients with Staphylococcus aureus bacteremia--reply." JAMA 313, no. 4 (January 2015): 420-421. (Letter)
Bloomfield, GS, Hogan, JW, Keter, A, Holland, TL, Sang, E, Kimaiyo, S, and Velazquez, EJ. "Blood pressure level impacts risk of death among HIV seropositive adults in Kenya: a retrospective analysis of electronic health records." BMC Infectious Diseases 14, no. 1 (December 2014). Full Text
Holland, T, Fowler, VG, and Shelburne, SA. "Invasive gram-positive bacterial infection in cancer patients." Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 59 Suppl 5 (November 2014): S331-S334. (Review)
Holland, TL, Arnold, C, and Fowler, VG. "Clinical management of Staphylococcus aureus bacteremia: a review." JAMA 312, no. 13 (October 2014): 1330-1341. (Review)
Bloomfield, GS, Hogan, JW, Keter, A, Holland, TL, Sang, E, Kimaiyo, S, and Velazquez, EJ. "Blood pressure level impacts risk of death among HIV seropositive adults in Kenya: a retrospective analysis of electronic health records." BMC infectious diseases 14 (January 2014): 284-.
Carugati, M, Bayer, AS, Miró, JM, Park, LP, Guimarães, AC, Skoutelis, A, Fortes, CQ, Durante-Mangoni, E, Hannan, MM, Nacinovich, F, Fernández-Hidalgo, N, Grossi, P, Tan, RS, Holland, T, Fowler, VG, Corey, RG, and Chu, VH. "High-dose daptomycin therapy for left-sided infective endocarditis: A prospective study from the international collaboration on endocarditis." Antimicrobial Agents and Chemotherapy 57, no. 12 (December 1, 2013): 6213-6222. Full Text
Chambers, ST, Murdoch, D, Morris, A, Holland, D, Pappas, P, Almela, M, Fernández-Hidalgo, N, Almirante, B, Bouza, E, Forno, D, Rio, AD, Hannan, MM, Harkness, J, Kanafani, ZA, Lalani, T, Lang, S, Raymond, N, Read, K, Vinogradova, T, Woods, CW, Wray, D, Corey, GR, Chu, VH, Clara, L, Sanchez, M, Nacinovich, F, Oses, PF, Ronderos, R, Sucari, A, Thierer, J, Casabé, J, Cortes, C, Altclas, J, Kogan, SS, Spelman, D, Athan, E, Harris, O, Kennedy, K, Tan, R, Gordon, D, Papanicolas, L, Eisen, D, and Grigg, L et al. "HACEK Infective Endocarditis: Characteristics and Outcomes from a Large, Multi-National Cohort." PLoS ONE 8, no. 5 (2013). Full Text
Bloomfield, GS, Hogan, JW, Keter, A, Holland, TL, Osanya, J, Sang, E, Kimaiyo, S, and Velazquez, EJ. "High Blood Pressure Increases Risk of Death Among Human Immunodeficiency Virus Seropositive Individuals in Kenya." CIRCULATION 126, no. 21 (November 20, 2012). Link to Item
Holland, TL, Thielman, NM, and Pearson, RD. "Chemotherapy of Bacterial, Fungal, and Viral Diseases." (December 1, 2011): 95-104. (Chapter) Full Text
Holland, TL, and Jr, VGF. "Vancomycin minimum inhibitory concentration and outcome in patients with Staphylococcus aureus bacteremia: Pearl or pellet?." Journal of Infectious Diseases 204, no. 3 (2011): 329-331. Full Text
Holland, TL, Woods, CW, and Joyce, M. "Antibacterial susceptibility testing in the clinical laboratory." Infect Dis Clin North Am 23, no. 4 (December 2009): 757-vii. (Review) Full Text Link to Item
Maina AN, Farris CM, Odhiambo A, Jiang J, Laktabai J, Armstrong J, Holland T, Richards AL, O’Meara WP. Q fever, scrub typhus, and rickettsial diseases in children, Kenya, 2011-2012. Emerg Infect Dis 2016;22(5):883-6.
Lumsden RH, Akwanalo C, Chepkwony S, Kithei A, Omollo V, Holland TL, Bloomfield GS, O’Meara WP. Clinical and geographic patterns of rheumatic heart disease in outpatients attending cardiology clinic in western Kenya. Int J Cardiology, August 2016